ChemInform Abstract: Rhodium-Mediated Intramolecular C—H Insertion: Probing the Geometry of the Transition State.
✍ Scribed by D. F. TABER; S. C. MALCOLM
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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Enantioselective Intramolecular C-H Insertion Route to a Key Intermediate for the Synthesis of Trinem Antibiotics. -The new route to the chiral azetidin-2-one title compound (III) is based on the Rh-catalyzed decomposition of the diazoester (I) and following intramolecular carbene C-H insertion. Th