1998 indole derivatives, isoindole derivatives indole derivatives, isoindole derivatives R 0140 19 -120 Quaternary Substituted PDE4 Inhibitors. Part 1. The Synthesis and in vitro Evaluation of a Novel Series of Oxindoles. -The synthesis and in vitro evaluation of a novel series of conformationally c
ChemInform Abstract: Quaternary Substituted PDE IV Inhibitors. Part 2. The Synthesis and in vitro Evaluation of a Novel Series of γ-Lactams.
✍ Scribed by C. HULME; K. MORIARTY; F.-C. HUANG; J. MASON; D. MCGARRY; R. LABAUDINIERE; J. SOUNESS; S. DJURIC
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 38 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. Part 2. Synthesis and Evaluation of (3R\*,5S\*)-ω-Substituted-3carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in vitro and in vivo. -A series of the title compounds is synthesized and evalua