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ChemInform Abstract: Quaternary Substituted PDE4 Inhibitors. Part 1. The Synthesis and in vitro Evaluation of a Novel Series of Oxindoles.

✍ Scribed by C. HULME; G. B. POLI; F.-C. HUANG; J. E. SOUNESS; S. W. DJURIC

Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

1998 indole derivatives, isoindole derivatives indole derivatives, isoindole derivatives R 0140 19 -120 Quaternary Substituted PDE4 Inhibitors. Part 1. The Synthesis and in vitro Evaluation of a Novel Series of Oxindoles. -The synthesis and in vitro evaluation of a novel series of conformationally constrained quaternary substituted oxindole analogues [cf. (IX),(XI)] of the Celltech PDE IV inhibitor CDP 840 is described. -(HULME, C.;

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