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ChemInform Abstract: Preparation of 2-O-(3-O-Carbamoyl-α-D-mannopyranosyl)-L- gulopyranose: Synthetic Study on the Sugar Moiety of Antitumor Antibiotic Bleomycin.

✍ Scribed by T. OSHITARI; S. KOBAYASHI


Book ID
112022492
Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
26
Category
Article
ISSN
0931-7597

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Synthesis of 2-O-(3-O-carbamoyl-α-d-mann
✍ Tetsuta Oshitari; Masakatsu Shibasaki; Takeshi Yoshizawa; Masahiro Tomita; Ken-i 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 892 KB

A new route to the disaccharide moiety (2-O-(3-O-carbamoyl-a-D-mannopyranosyl)-L-gulopyranose) of the antitumor agent bleomycin was develolfed. Both the L-gulose synthon 21 and the 3-O-carbamoyl-D-mannose segment 30 were prepared from D-mannose in a regioselective manner by applying stannylene aceta