Synthesis of 2-O-(3-O-carbamoyl-α-d-mann
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Tetsuta Oshitari; Masakatsu Shibasaki; Takeshi Yoshizawa; Masahiro Tomita; Ken-i
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Article
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1997
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Elsevier Science
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French
⚖ 892 KB
A new route to the disaccharide moiety (2-O-(3-O-carbamoyl-a-D-mannopyranosyl)-L-gulopyranose) of the antitumor agent bleomycin was develolfed. Both the L-gulose synthon 21 and the 3-O-carbamoyl-D-mannose segment 30 were prepared from D-mannose in a regioselective manner by applying stannylene aceta