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ChemInform Abstract: Polymer-Supported Reagents: Facile Synthesis of β-Oxoalkyl ( Acetonyl) Esters of Carboxylic Acids.

✍ Scribed by M. M. SALUNKHE; A. R. SANDE; A. S. KANADE; P. P. WADGAONKAR


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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Aziridine 2-Carboxylate Ester Mediated Asymmetric Synthesis of α-Alkyl β-Amino Acids. -Highly stereoselective reductive ring opening of the N-tosylaziridines (II) with LiAlH4 followed by oxidation of the syn-amino alcohols (III) provides an efficient entry to the asymmetric synthesis of αmethyl β-am