Efficient Chemoenzymatic Synthesis of (2S,3S)-3-Hydroxyleucine Mediated by Immobilized Penicillin G Acylase. -The title enzyme is used for the resolution of the racemate (Β±)-(V) to obtain the optically pure Ξ²-hydroxy-Ξ±-amino acid (+)-(VI), an important constituent of a range of naturally occurring
ChemInform Abstract: Penicillin G Acylase Mediated Synthesis of the Enantiopure (S)-3-Amino-azetidin-2-one.
β Scribed by G. CAINELLI; D. GIACOMINI; P. GALLETTI; M. DACOL
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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