Synthesis of (-)-3-Amino-3-deoxyquinic Acid. -The title acid (X) is prepared in nine steps from quinic acid (I) in 14% overall yield. Its importance for the biosynthesis of 3-amino-5-hydroxybenzoic acid, the precursor of mC 7 N-units in ansamycin and mitomycin antibiotics is discussed. -
ChemInform Abstract: Stereospecific Synthesis of the Amino Acid, (S)-2-Amino-(Z)-3,5-hexadienoic Acid.
β Scribed by S. CAMERON; B. P. S. KHAMBAY
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Stereospecific Synthesis of the Amino Acid, (S)-2-Amino-(Z)-3,5hexadienoic Acid. -The first synthesis of the title hexadienoic amino acid (VII), a key component of the insecticidal dipeptide isolated from the Colorado beetle, starting from protected serine aldehyde (I) is reported. -(CAMERON,
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