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ChemInform Abstract: Efficient Chemoenzymatic Synthesis of (2S,3S)-3-Hydroxyleucine Mediated by Immobilized Penicillin G Acylase.

✍ Scribed by N. W. FADNAVIS; M. SHARFUDDIN; S. K. VADIVEL; U. T. BHALERAO

Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Efficient Chemoenzymatic Synthesis of (2S,3S)-3-Hydroxyleucine Mediated by Immobilized Penicillin G Acylase.

-The title enzyme is used for the resolution of the racemate (Β±)-(V) to obtain the optically pure Ξ²-hydroxy-Ξ±-amino acid (+)-(VI), an important constituent of a range of naturally occurring cyclo-depsipeptides. -(FADNAVIS, N. W.; SHARFUDDIN,

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