ChemInform Abstract: Parallel Synthesis of Novel Heteroaromatic Acromelic Acid Analogues from Kainic Acid.
β Scribed by Jack E. Baldwin; Andrew M. Fryer; Gareth J. Pritchard
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 37 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
A Formal Synthesis of (-)-Ξ±-Kainic Acid. -Starting from Lpyroglutamic acid (-)-(I), the known precursor (-)-(XVI) for the synthesis of the title compound is presented. The key step in this approach is the SmI 2 -mediated ketyl radical cyclization of the enecarbamate (X). Under irradiation condition