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ChemInform Abstract: Organocatalyzed Enantioselective Synthesis of 2-Amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates.

โœ Scribed by Naresh Ramireddy; Santhi Abbaraju; Cong-Gui Zhao


Book ID
112042866
Publisher
John Wiley and Sons
Year
2012
Weight
40 KB
Volume
43
Category
Article
ISSN
0931-7597

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Organocatalyzed synthesis of 2-amino-8-o
โœ Derong Ding; Cong-Gui Zhao ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 279 KB

2-Amino-8-oxo-tetrahydro-4H-chromene-3-carbonitriles were synthesized for the first time from a tandem Michael addition - cyclization reaction between cyclohexane-1,2-dione and benzylidenemalononitriles. An enantioselective synthesis of these compounds was achieved in moderate ee values (up to 63% e