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ChemInform Abstract: Nucleosides and Nucleotides. Part 146. New Neplanocin Analogues. Part 5. A Potent Adenosylhomocysteine Hydrolase Inhibitor Lacking Antiviral Activity. Synthesis and Antiviral Activity of 6′-Carboxylic Acid Derivatives of Neplanocin A.

✍ Scribed by T. OBARA; S. SHUTO; Y. SAITO; M. TORIYA; K. OGAWA; S. YAGINUMA; S. SHIGETA; A. MATSUDA


Book ID
112039293
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Nucleosides and Nuc
✍ A. MATSUDA; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Nucleosides and Nucleotides. Part 154. New Neplanocin Analogues. Part 8. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A. -Reaction of the aldehyde (I) with ethynylmagnesium bromide gives the corresponding 6'-ethynyl derivative as a diastereomeric