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ChemInform Abstract: Novel C-2 Substituted Carbapenem Derivatives. Part 2. Synthesis and Structure-Activity Relationships of Isoxazolin-2-yl, Isoxazolidin-2-yl, and 2-Pyrazolin-2-yl Carbapenems Generated Using 1,3-Dipolar Cycloaddition Chemistry.

✍ Scribed by G. BURTON; G. J. CLARKE; J. D. DOUGLAS; A. J. EGLINGTON; C. H. FRYDRYCH; J. D. HINKS; N. W. HIRD; E. HUNT; S. F. MOSS; A. NAYLOR; N. H. NICHOLSON; M. J. PEARSON


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel C-2 Substitut
✍ G. BURTON; N. J. C. CLEAR; A. J. EGLINGTON; A. W. GUEST; E. HUNT; A. NAYLOR; M. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 1 views

Novel C-2 Substituted Carbapenem Derivatives. Part 1. Synthesis and Biological Activity of Non-Aromatic Heterocyclic Derivatives. -A series of new carbapenems, e.g. (III), (XI), and (XIV), is investigated for biological activity. It is shown that (S)-stereochemistry at the C-2 side chain and the int