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ChemInform Abstract: Synthesis and Structure—Activity Relationship of 2-(Aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine Derivatives: A Novel Series of 5-HT2A/2C Receptor Antagonists. Part 1.

✍ Scribed by J. Ignacio Andres; et al. et al.


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis, Structur
✍ Fabrice Lacan; Martine Varache-Lembege; Joseph Vercauteren; Jean-Michel Leger; B 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB

Synthesis, Structural Characterization and Thromboxane A 2 Receptor Antagonistic Activity of 3-Substituted 2-[(Arylsulfonyl)imino]-2,3-dihydrothiazolyl Derivatives. -Seven new title derivatives such as (I) are prepared by the Hantzsch synthesis. Compounds (I) show significant binding affinities in