Nostocyclin, a novel 3-amino-6-hydroxy-2
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Kunimitsu Kaya; Tomoharu Sano; Kenneth A. Beattie; Geoffrey A. Codd
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Article
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1996
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Elsevier Science
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French
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Nostocyclin, a novel 3-amino-6-hydroxy-2-piperidone-containing cyclic peptide was isolated from a hepatotoxic strain of cyanobacterium Nostoc sp. Nostocyclin is non-toxic in acute in vivo bioassays, but inhibits protein phosphatase-1 activity at high concentration in vitro.