ChemInform Abstract: New Synthetic Strategies to Vitamin D Analogues Modified at the Side Chain and D Ring. Synthesis of 1α,25-Dihydroxy-16-ene-vitamin D3 and C-20 Analogues.
✍ Scribed by Maria de los Angeles Rey; Jose Antonio Martinez-Perez; Ana Fernandez-Gacio; Koen Halkes; Yagamare Fall; Juan Granja; Antonio Mourino
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 43 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Efficient and Versatile Synthesis of A-Ring Precursors of 1α,25-Dihydroxy-Vitamin D3 and Analogues. Application to the Synthesis of Lythgoe-Roche Phosphine Oxide. -Starting from 1-carvone (I) an efficient approach to the Lythgoe-Roche phosphine oxide (XII), an important vitamin D synthon, is report