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ChemInform Abstract: Efficient Synthesis of the A-Ring Phosphine Oxide Building Block Useful for 1α,25-Dihydroxy Vitamin D3 and Analogues.

✍ Scribed by Andrzej R. Daniewski; Lisa M. Garofalo; Stanley D. Hutchings; Marek M. Kabat; Wen Liu; Masami Okabe; Roumen Radinov; George P. Yiannikouros


Publisher
John Wiley and Sons
Year
2010
Weight
40 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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ChemInform Abstract: Efficient and Versa
✍ A. MOURINO; M. TORNEIRO; C. VITALE; S. FERNANDEZ; J. PEREZ-SESTELO; S. ANNE; C. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

Efficient and Versatile Synthesis of A-Ring Precursors of 1α,25-Dihydroxy-Vitamin D3 and Analogues. Application to the Synthesis of Lythgoe-Roche Phosphine Oxide. -Starting from 1-carvone (I) an efficient approach to the Lythgoe-Roche phosphine oxide (XII), an important vitamin D synthon, is report