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ChemInform Abstract: Isoxazoline GPIIb/IIIa Antagonists Bearing a Phosphoramidate

โœ Scribed by John Wityak; A. Ewa Tobin; Shaker A. Mousa; Ruth R. Wexler; Richard E. Olson

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
30
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Isoxazoline GPIIb/IIIa Antagonists Bearing a Phosphoramidate -[synthesis and in vitro antiplatelet efficacy of a series of novel phosphoramidates (I) (6 examples)]. -(WITYAK, JOHN;

๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: The Enantiospecific
ChemInform Abstract: The Enantiospecific Synthesis of an Isoxazoline. A RGD Mimic Platelet GPIIb/IIIa Antagonist.
โœ L. ZHANG; J. C. CHUNG; T. D. COSTELLO; I. VALVIS; P. MA; S. KAUFFMAN; R. WARD ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

The Enantiospecific Synthesis of an Isoxazoline. A RGD Mimic Platelet GPIIb/IIIa Antagonist. -The crystalline compound (VI), is synthesized on a multikilogram scale in 8 steps in 37% overall yield and ยฟ99.