Platelet-membrane surface receptors are important targets for pharmacologic intervention in cardiovascular disease. Among these, glycoprotein (GP) IIb-IIIa is dominant and integrally involved in platelet aggregation and thrombus formation. When activated, GPIIb-IIIa binds soluble fibrinogen (Fb) in
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ChemInform Abstract: Orbofiban: An Orally Active GPIIb/IIIa Platelet Receptor Antagonist
โ Scribed by Nancy S. Nicholson; Norman A. Abood; Susan G. Panzer-Knodle; Leo G. Frederick; Jimmy D. Page; Anita K. Salyers; Osman D. Suleymanov; James A. Szalony; Beatrice B. Taite; Robert J. Anders
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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