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ChemInform Abstract: Inhibiting the Dimerization of HIV-1 Protease

โœ Scribed by R. ZUTSHI; M. D. SHULTZ; L. ULYSSE; R. LUTGRING; P. BISHOP; B. SCHWEITZER; K. VOGEL; J. FRANCISKOVICH; M. WILSON; J. CHMIELEWSKI


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
29
Category
Article
ISSN
0931-7597

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Reaction coordinate for the irreversible inhibition of the HIV-1 protease ลฝ . by epoxy alkylating agent has been examined by ab initio HFr6-31G d calculations, ลฝ . semiempirical molecular orbital MO calculations, while the effect of polar macromolecular environment was included on the solvent reacti