Inhibitors of HIV protease: Unique non-p
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Bradley D. Tait; John Domagala; Edmund L. Ellsworth; Donna Ferguson; Christopher
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Article
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1996
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John Wiley and Sons
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English
โ 405 KB
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New templates were designed and prepared which straddle the active site of HIV-1 protease. These templates were designed to be 'flexible scaffolds' upon which substituents could be appended to fill the pockets of HIV protease. The new templates prepared and analysed were 4-hydroxy-5H-furan-2-ones, 4