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Cross-linked Peptoid-Based Dimerization Inhibitors of HIV-1 Protease

✍ Scribed by Song-Gil Lee; Jean Chmielewski


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
279 KB
Volume
11
Category
Article
ISSN
1439-4227

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Physiologically based pharmacokinetics o
✍ Akiko Kiriyama; Tomoyuki Nishiura; Hirokazu Yamaji; Kanji Takada πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 134 KB πŸ‘ 1 views

The effects of dose on the pharmacokinetic characteristics of KNI-272 were evaluated in rats after intravenous (iv) administration. The plasma kinetics of KNI-272 were dose-independent within a dose range of 1.0 to 10.0 mg/kg. However, when the dose was increased to 50.0 mg/kg, the area under the pl