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ChemInform Abstract: Identification of Biaryl Sulfone Derivatives as Antagonists of the Histamine H3 Receptor: Discovery of (R)-1-(2-(4′- (3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916).

✍ Scribed by Graeme Semple; et al. et al.

Book ID
112044245
Publisher
John Wiley and Sons
Year
2012
Weight
19 KB
Volume
43
Category
Article
ISSN
0931-7597

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✍ Wolfgang Haap; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

## Abstract Compound (I) is found to be a potent, selective and orally bioavailable fXa inhibitor based on a pyrrolidine scaffold.