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ChemInform Abstract: General Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxaline Derivatives Catalyzed by Iridium-Difluorphos: Unusual Halide Effect and Synthetic Application.

✍ Scribed by Damien Cartigny; Farouk Berhal; Takuto Nagano; Phannarath Phansavath; Tahar Ayad; Jean-Pierre Genet; Takashi Ohshima; Kazushi Mashima; Virginie Ratovelomanana-Vidal

Book ID: 115552242
Publisher: John Wiley and Sons
Year: 2012
Weight: 58 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201237169

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General Asymmetric Hydrogenation of 2-Al

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ChemInform Abstract: Iridium-Difluorphos

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## Abstract A highly efficient and general iridium‐difluorphos‐catalyzed asymmetric hydrogenation of diverse 2‐alkyl‐ and 2‐aryl‐substituted quinoxalines into biologically and pharmaceutically relevant 2‐substituted‐1,2,3,4‐tetrahydroquinoxaline units has been developed. High isolated yields and ex

ChemInform Abstract: Unprecedented Halid

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