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ChemInform Abstract: Functionalization by Metalation of Fluoropyrazine. Diazines. Part 21.

โœ Scribed by N. PLE; A. TURCK; A. HEYNDERICKX; G. QUEGUINER

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: First Functionaliza
ChemInform Abstract: First Functionalization by Metallation of the Benzene Moiety of Quinazolines. Diazines. Part 19.
โœ N. PLE; A. TURCK; V. CHAPOULAUD; G. QUEGUINER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 35 KB

First Functionalization by Metallation of the Benzene Moiety of Quinazolines. Diazines. Part 19. -4-Substituted quinazolines are found to undergo unexpected regioselective lithiation at C-8. This offers an efficient pathway to a large number of new substituted quinazolines which cannot be easily pr