ChemInform Abstract: First Metalation of Iodo Diazines. Iodo and Nitrogen Directed Metalations. Diazines. Part 22.
β Scribed by N. PLE; A. TURCK; A. HEYNDERICKX; G. QUEGUINER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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First Functionalization by Metallation of the Benzene Moiety of Quinazolines. Diazines. Part 19. -4-Substituted quinazolines are found to undergo unexpected regioselective lithiation at C-8. This offers an efficient pathway to a large number of new substituted quinazolines which cannot be easily pr