ChemInform Abstract: Fluorescent Signalling of the Brain Neurotransmitter γ- Aminobutyric Acid and Related Amino Acid Zwitterions.
✍ Scribed by A. P. DE SILVA; H. Q. N. GUNARATNE; C. MCVEIGH; G. E. M. MAGUIRE; P. R. S. MAXWELL; E. O'HANLON
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Fluorescent Signalling of the Brain Neurotransmitter γ-Aminobutyric Acid and Related Amino Acid Zwitterions.
-Compound (V) combining an aza-crown ether unit and a guanidinium receptor moiety is used as fluorescent sensor. (V) shows a significant fluorescence enhancement with γ-aminobutyric acid in mixed aqueous solution (no yields given). -(DE
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Syntheses of Novel Piperidin-4-ylphosphinic Acid, and Piperidin-4-ylphosphonic Acid Analogues of the Inhibitory Neurotransmitter 4-Aminobutyric Acid (GABA). -The novel acids (V)-(VIII) are synthesized utilizing a sequential Pudovik addition followed by a modified Barton deoxygenation and acidic hydr