ChemInform Abstract: Enzyme-Mediated Synthesis of (R)- and (S)-α-Ionone.
✍ Scribed by Elisabetta Brenna; Claudio Fuganti; Piero Grasselli; Mara Redaelli; Stefano Serra
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Enzyme-Mediated Synthesis of (R)-and (S)-α-Ionone.
-Two approaches to the title compounds are presented, which differ only by interchanging the application of traditional techniques of fractional recrystallization and enzyme-mediated reactions. The other two diastereomers of α-ionol are also synthesized using a Mitsunobu reaction of (IV) or its corresponding enantiomer.
📜 SIMILAR VOLUMES
See [14a]. BF,.Et,O-Catalyzed benzyloxylation of 3 led to partially racemized 4 (cu. 70%) [14b]. For other recent bcnzyloxylations of ~,P-unsaturated carbonyl compounds, see [14c].
Lipase-Mediated Synthesis of the Enantiomeric Forms of 4,5-Epoxy-4,5-dihydro-α-ionone and 5,6-Epoxy-5,6-dihydro-β-ionone. A New Direct Access to Enantiopure (R)-and (S)-α-Ionone. -In continuation of a recent study a lipase-mediated approach to optically active α-ionone starting from its racemate is
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