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ChemInform Abstract: Enantioselective Synthesis of Isoindolines: An Organocatalyzed Domino Process Based on the Aza-Morita—Baylis—Hillman Reaction.

✍ Scribed by Shinobu Takizawa; Naohito Inoue; Shuichi Hirata; Hiroaki Sasai

Publisher
John Wiley and Sons
Year
2011
Weight
38 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: An Enantioselective
ChemInform Abstract: An Enantioselective Organocatalyzed Aza-MBH Domino Process: Application to the Facile Synthesis of Tetrahydropyridines.
✍ Shinobu Takizawa; Naohito Inoue; Hiroaki Sasai 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 42 KB 👁 2 views

## Abstract A chiral BINOL‐based acid‐base catalyst is found to promote the aza‐Morita—Baylis—Hillman domino reaction of α,β‐unsaturated carbonyl compounds and N‐tosylimines to yield optically active tetrahydropyridines with good e.e.‐values.