Enantioselective synthesis of enantiomer
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Gy.M. KeserΓΌ; M. NΓ³grΓ‘di; J. RΓ©tey; J. Robinson
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Article
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1997
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Elsevier Science
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French
β 335 KB
Ab~ract: (R)-l,3-2H2-Prop-2-yn-l-ot [(R)-21 was obtained by enzymatic deuteration of prop-2-yn-l-ol. Methoxymethylation and thermal rearrangement of (R)-2 gave (33-(1,3-2H2)allene (33-1, while reaction of (R)-l-2H2-prop-2-yn-l-ol [(R)-2a] with MeOC2H2CI followed by thermolysis afforded (R)-(l,3-2H2