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ChemInform Abstract: Synthesis of Enantiomerically Pure 3-Fluoromethylthreonines from (S)-1- Fluoro-3-tolylsulfinylacetone.

โœ Scribed by A. ARNONE; D. GESTMANN; S. V. MEILLE; G. RESNATI; G. SIDOTI


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Enantiomeric Synthe
โœ J. H. HONG; K. LEE; Y. CHOI; C. K. CHU ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 36 KB ๐Ÿ‘ 1 views

Enantiomeric Synthesis of 3'-Fluoro-Apionucleosides Using Claisen Rearrangement. -Starting from the triol (I), readily available from 1,2-O-isopropylidene-D-glyceraldehyde, an enantiomeric synthesis of 3'-fluoroapionucleosides such as (X) and (XI) is accomplished. The route to the key-intermediate