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ChemInform Abstract: Enantioselective Nucleophilic Formylation and Cyanation of Conjugated Enones via Michael Addition of Formaldehyde SAMP-Hydrazone.

✍ Scribed by J.-M. LASSALETTA; R. FERNANDEZ; E. MARTIN-ZAMORA; E. DIEZ


Book ID
112039741
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Michael
✍ D. Enders; Pascal Teschner; Robert Groebner; Gerhard Raabe πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

Asymmetric Michael Additions via 6-and 7-Membered Lactone SAMP-Hydrazones: Diastereo-and Enantioselective Synthesis of Substituted Lactone Esters. -High asymmetric inductions are achieved in the Michael addition of hydrazones (I) to Ξ±,Ξ²-unsaturated esters (II). Removal of the chiral auxiliary by ozo