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ChemInform Abstract: Diastereo- and Enantioselective Synthesis of β-Amino Acids via SAMP Hydrazones and Hetero Michael Addition Using TMS-SAMP as a Chiral Equivalent of Ammonia

✍ Scribed by D. ENDERS; W. BETTRAY; J. SCHANKAT; J. WIEDEMANN


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Michael
✍ D. Enders; Pascal Teschner; Robert Groebner; Gerhard Raabe 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

Asymmetric Michael Additions via 6-and 7-Membered Lactone SAMP-Hydrazones: Diastereo-and Enantioselective Synthesis of Substituted Lactone Esters. -High asymmetric inductions are achieved in the Michael addition of hydrazones (I) to α,β-unsaturated esters (II). Removal of the chiral auxiliary by ozo