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ChemInform Abstract: Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by a . beta.-Amino Disulfide Derived from L-Proline.

✍ Scribed by C. L. GIBSON


Book ID
112034629
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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A (+)-3-carene derived aminoalcohol was successfully used as a chiral ligand in the catalytic enantioselective diethylzinc addition to various aldehydes. Very high enantiomeric excess (up 98% in 1-(2-methoxyphenyl)-1-propanol) was obtained. A plausible mechanism has been suggested for the observed e