Enantioselective alkylation of N-diphenylphosphinylimine with dialkylzincs using monomeric chiral amino alcohols and copolymerized chiral amino alcohols as chiral ligands afforded N-diphenylphosphinylamines with high enantiomeric excess (EE). Among monomeric chiral ligands, N-vinylbenzylephedrine wa
ChemInform Abstract: Enantioselective Addition of Dialkylzincs to N-Diphenylphosphinylimines Using Polymer-Supported N,N-Dialkylnorephedrines as Chiral Ligands.
β Scribed by T. SUZUKI; T. SHIBATA; K. SOAI
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Cinchona alkaloids are utilized as chiral ligands to promote the enantioselective addition of dialkylzinc to __N__βdiphenylphosphinylimines affording enantiomerically enriched __N__βdiphenylphosphinylamines in up to 91% __ee__.
N-Alkyl-N-vinylbenzylnorephedrines and Their Copolymers as Chiral Ligands for the Highly Enantioselective Ethylation of N-Diphenylphosphinylimine. -Monomeric (as mixtures of m-and p-vinyl isomers) and polymeric norephedrines (I) and (III) as well as their N-methylated antipodes ( cf. (II)) are teste