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ChemInform Abstract: Enamines in Heterocyclic Synthesis: A Novel Simple and Efficient Route to Condensed Pyridazines.

โœ Scribed by Elham S. Darwish; Mahmoud A. Abdelrahman; Abdellatif M. Salaheldin

Publisher
John Wiley and Sons
Year
2011
Weight
33 KB
Volume
42
Category
Article
ISSN
0931-7597

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A Simple and Efficient Synthetic Route to Chiral Isopavines. Synthesis of (-)-O-Methylthalisopavine and (-)-Amurensinine. -The key steps in the synthesis of the title compounds (VIII) are stereoselective addition of the Grignard reagent (II) to the imines (I) and a novel one-pot double-intramolecul