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ChemInform Abstract: Electrooxidative Desulfurization/Chlorination. A Facile Synthesis of 4-Chloro-2-azetidinones, a Potent Intermediate for Carbapenems.

✍ Scribed by Manabu Kuroboshi; Masayoshi Miyada; Syoichi Tateyama; Hideo Tanaka


Publisher
John Wiley and Sons
Year
2009
Weight
26 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Practical Synthes
✍ C. YANG; N. YASUDA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 1 views

A Practical Synthesis of 3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(2R)-4-halo-3-oxo-2-butyl]azetidinone, a Versatile Intermediate for Carbapenem Antibiotics. -The readily available carboxylic acid (I) is converted efficiently by a three-step procedure into the title compounds such as (VI). Desily