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ChemInform Abstract: Stereocontrolled Synthesis of 4-Acetoxy-2-azetidinone via Double Azetidinone Ring Formation: A Useful Precursor of Carbapenem and Penem Antibiotics.

โœ Scribed by H. A. KWON; M. J. LEE; I. H. LEE; S. J. LEE; T. H. YOON; T. S. HWANG


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Practical Synthes
โœ C. YANG; N. YASUDA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

A Practical Synthesis of 3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(2R)-4-halo-3-oxo-2-butyl]azetidinone, a Versatile Intermediate for Carbapenem Antibiotics. -The readily available carboxylic acid (I) is converted efficiently by a three-step procedure into the title compounds such as (VI). Desily