## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
ChemInform Abstract: Efficient One-Pot Formation of Substituted γ-Amino Acids.
✍ Scribed by Mardia T. El-Sayed; Muhammad Abbas; Andreas Hilgeroh
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 30 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
A series of novel substituted γ‐amino acids (III) is prepared by an one‐pot reaction of imines (I) and a homoenolate, generated in situ from the hemiacetal (II).
📜 SIMILAR VOLUMES
Mono-N-ethylated h-amino acid esters are obtained in high yields using reductive amination procedures. Formation of imine is achieved by excess of acetaldehyde, followed by removal of acetaldehyde and reduction by NaBH(OAc) 3 . The elaborated one-pot synthesis allows for the efficient synthesis of s
Facile Stereoselective Synthesis of γ-Substituted γ-Amino Acids from the Corresponding α-Amino Acids. -The mild and short procedure presented is compatible with common side-chain protecting groups, sensitive functionalities and preserves the chirality of the starting α-amino acid.
Efficient Synthesis of γ-Oxo-and γ-Hydroxy-α-amino Acids. -Reduction of aminoester (Va) with Zn(BH 4 ) 2 permits intermediate isolation of the γ-hydroxy derivative, which is converted to lactone (IX) during silica gel chromatography. -(MERLA, B.;
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v