𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Design, Synthesis and Discovery of 1-(2-(6-Chloro-3-methylsulfonyl)-naphthyl)-1H-pyrazole-5-carboxylamides as Highly Potent Factor Xa Inhibitors.

✍ Scribed by Zhaozhong Jon Jia; Robert Murry Scarborough; Penglie Zhang; Sherin Halfon; Ann Elizabeth Arfsten; Uma Sinha; Bing-Yan Zhu

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
41
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Discovery of a Fact
ChemInform Abstract: Discovery of a Factor Xa Inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic Acid 3-[(5-Chloro-pyridin-2-yl)-amide] 4-{[2-Fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a Clinical Candidate.
✍ Wolfgang Haap; et al. et al. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 23 KB

## Abstract Compound (I) is found to be a potent, selective and orally bioavailable fXa inhibitor based on a pyrrolidine scaffold.