ChemInform Abstract: Design and Synthesis of Thiol Containing Inhibitors of Matrix Metalloproteinases.
β Scribed by Cynthia A. Fink; J. Eric Carlson; Charles Boehm; Patricia McTaggart; Ying Qiao; John Doughty; Vishwas Ganu; Richard Melton; Ronald Goldberg
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors. -A novel series of matrix metalloproteinase inhibitors such as (I) based on 1,3-piperazine is synthesized and evaluated for the inhibition of callagenase-1, stromelysin, matrilysin, and gelatinase-B. The most active compound is (Ib).
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