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ChemInform Abstract: Design and Synthesis of Piperazine-Based Matrix Metalloproteinase Inhibitors.

✍ Scribed by Biswanath De; et al. et al.


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design, Synthesis,
✍ Michael G. Natchus; et al. et al. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Discovery of Potent
✍ S. PIKUL; ET AL. ET AL. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB πŸ‘ 2 views

Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors. -A novel series of matrix metalloproteinase inhibitors such as (I) based on 1,3-piperazine is synthesized and evaluated for the inhibition of callagenase-1, stromelysin, matrilysin, and gelatinase-B. The most active compound is (Ib).