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ChemInform Abstract: Convenient One-Pot Synthesis of trans-1,2-Diaryloxiranes from the Direct Coupling of Benzyl Halides.

✍ Scribed by Freeman M. Wong; Yee Man Chan; David X. Chen; Weiming Wu

Publisher
John Wiley and Sons
Year
2011
Weight
24 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: One-Pot Synthesis of Imidazo[1,2-a]pyridines from Benzyl Halides or Benzyl Tosylates, 2-Aminopyridines and Isocyanides.
✍ Mehdi Adib; Ehsan Sheikhi; Narjes Rezaei πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 2 views

## Abstract Benzyl halides (I) or ‐tosylates (V) are oxidized to aldehydes under mild Kornblum conditions which then undergo a three‐component reaction with various 2‐aminopyridines (II) and isocyanides (III) to afford title compounds (IV)/ (VI) in high yields.