ChemInform Abstract: One-Pot Synthesis of Imidazo[1,2-a]pyridines from Benzyl Halides or Benzyl Tosylates, 2-Aminopyridines and Isocyanides.
β Scribed by Mehdi Adib; Ehsan Sheikhi; Narjes Rezaei
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 33 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
Benzyl halides (I) or βtosylates (V) are oxidized to aldehydes under mild Kornblum conditions which then undergo a threeβcomponent reaction with various 2βaminopyridines (II) and isocyanides (III) to afford title compounds (IV)/ (VI) in high yields.
π SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract Simple and efficient methods for the synthesis of the title compounds (II), by using available and inexpensive reagents, is developed in the ionic liquid Bu~4~NBr as a green solvent.