ChemInform Abstract: Convenient Approaches to 4-Trifluoromethylpyridine.
β Scribed by Biao Jiang; Wennan Xiong; Xiaobing Zhang; Fangjiang Zhang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
Reaction of Ξ±,Ξ²-unsaturated trifluoromethyl ketones (I) with primary enamines in the presence of POCl 3 and pyridine adsorbed on silica gel and following oxidation of the resulting dihydropyridines provides a high-yielding synthesis of title compounds (III) (16 examples). -(KATSUYAMA, I.; OGAWA,