ChemInform Abstract: Conformational Changes of Non-B DNA
β Scribed by Jungkweon Choi; Tetsuro Majima
- Book ID
- 102071695
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 10 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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The electrophoretic mobility of calf thymus DNA has been measured in aqueous buffered solutions as a function of pH. In the pH range 3.7-3.0, two electrophoretic species appear. The faster one migrates with the mobility of native DNA, the slower one migrates with a mobility close to that of thermall
## Abstract Repetitive DNA motifs may fold into nonβB DNA structures, including cruciforms/hairpins, triplexes, slipped conformations, quadruplexes, and leftβhanded ZβDNA, thereby representing chromosomal targets for DNA repair, recombination, and aberrant DNA synthesis leading to repeat expansion