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Non-B DNA Conformations, Genomic Rearrangements, and Human Disease

✍ Scribed by Bacolla, Albino (author);Wells, Robert D. (author)


Book ID
111652827
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2004
Tongue
English
Weight
210 KB
Volume
279
Category
Article
ISSN
0021-9258

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Non-B DNA conformations as determinants
✍ Albino Bacolla; Robert D. Wells πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 207 KB

## Abstract Repetitive DNA motifs may fold into non‐B DNA structures, including cruciforms/hairpins, triplexes, slipped conformations, quadruplexes, and left‐handed Z‐DNA, thereby representing chromosomal targets for DNA repair, recombination, and aberrant DNA synthesis leading to repeat expansion