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ChemInform Abstract: Chemoenzymatic Synthesis of (R)-(+)-Patulolide A, a Macrolide Antibiotic Isolated from Penicillium urticae.

✍ Scribed by M. KAMEZAWA; M. KITAMURA; H. NAGAOKA; H. TACHIBANA; T. OHTANI; Y. NAOSHIMA

Book ID
112037487
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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## Abstract (__R__)‐(+)‐Patulolide A [(__R__)‐1] was synthesized with an enantiomeric purity of almost 100% e.e. by a two‐step lipase‐catalyzed enantioselective hydrolysis of racemic thioketal acetate (Β±)‐11.

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