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ChemInform Abstract: Chelation-Controlled Aldol Reaction of Silyl Dienolate Derived from Ethyl Crotonate with a Chiral Aldehyde.

✍ Scribed by Seunguk Paik

Book ID: 101884135
Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199930038

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✦ Synopsis

Chelation-Controlled Aldol Reaction of Silyl Dienolate Derived from Ethyl Crotonate with a Chiral Aldehyde. -Asymmetric aldol reaction of a chiral alkoxyaldehyde (II) with silyl dienolate (III) derived from methyl crotonate is achieved with moderate to high diastereoselection in the presence of Lewis acids such as TiCl 4 and ZnCl 2 . -(PAIK, SEUNGUK; Bull. Korean

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