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ChemInform Abstract: Catalytic Enantioselective Alkylation of Benzaldehyde with Diethylzinc Using Chiral Nonracemic (Thio)phosphoramidates.

✍ Scribed by R. HULST; H. HERES; K. FITZPATRICK; N. C. M. W. PEPER; R. M. KELLOGG


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Catalytic Enantioselective Alkylation of Benzaldehyde with Diethylzinc Using Chiral Nonracemic (Thio)phosphoramidates.

-Diethylzinc undergoes enantioselective addition reaction to benzaldehyde in the presence of chiral (thio)phosphoramidate catalysts.

Addition of titanium tetraisopropoxide increases the yield as well as the stereoselectiv-


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